Application

DLAM-I^δ1V^proS-¹³CH₃ is an optimized kit to produce proteins with ¹³CH₃ isotopomer on the methyl groups of isoleucine and valine. This kit has been tested with protein isotopic labeling in E. coli. It is used in NMR investigations of the structure, dynamics and function of challenging biological systems at atomic resolution. Introduction of ¹³C -labeled methyl group in highly deuterated background enhances the resolution of methyl-TROSY spectra.

For detection of long-range nOes or for the NMR study of large proteins

General description

DLAM-I^δ1V^proS-¹³CH₃ kit has ¹³CH₃ isotopomer precursors and contains protocol instructions for creation of isotopically-labeled proteins.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.